Adenovirus genomics and taxonomy     Comparative virology     Fish herpesviruses

     Balázs Harrach            Mária Benkö          Máté Jánoska+         Gyözö Kaján                Andor Doszpoly                        Endre Kovács

pictures      publications      adenovirus taxonomy      table of sequenced AdVs      Blast search for AdVs      Blast search for HAdV hexon loop2

 

Our friend Máté Jánoska died on the 6th of January, 2010.
He was a promising scientist, he helped everybody and was always happy. We all miss him very much.

 

Molecular virology team

 

 

Mária Benkö DVM, PhD, professor, team leader (publications+citations)

 

Andor Doszpoly biologist, PhD student

Noémi Erdei biologist, PhD student

Gyözö Kaján DVM, PhD student

Endre Kovács biologist, PhD student

Judit Pénzes BSc, biology student

Gabriella Skoda BSc, biology student

Zoltán Tarján BSc, biology student

 

Comparative virology team

Balázs Harrach DVM, PhD, DSc, professor, team leader (publications+citations)

Monika Ballmann PhD student

 

Márton Vidovszky junior scientist, PhD student

 

Laura Panto biologist

 

Vibeke Halvorsen veterinary student (from Norway)

 

Silje Fabrin Lagstad veterinary student (from Norway)

 

 

Earlier members

 

The main interest of the research group is the molecular biological characterization of animal adenoviruses and herpesviruses. Adenovirus research has long tradition in the Hungarian veterinary virology. In the 60's, several bovine adenovirus (BAdV) strains exhibiting remarkable differences in their biological properties (such as replication ability, serological reactivity, etc.) compared to the human and other mammalian adenoviruses were isolated in Hungary. In the passed decades, our group characterized the genome of these viruses and proved their reptilian origin. Based on the DNA sequences, the recognition of a unique genomic organization (Both et al.), and the results of phylogenetic analyses, these and similar viruses indeed form a separate taxon equivalent to the earlier established two (Mastadenovirus & Aviadenovirus) genera within the family Adenoviridae. By now, we have established three new genera: Atadenovirus, Siadenovirus and Ichtadenovirus. A large number of exotic animal adenovirus types are studied for comparative purposes. We sequence the genomes of several adenoviruses including ones that could not be isolated and propagated. Fish herpesviruses and herpesviruses of exotic animals are also being studied on the molecular level.

 

9th International Adenovirus Meeting - Dobogókő (in the hills, 30 km from Budapest), April 26-30, 2009

 

8th International Congress of Veterinary Virology - Budapest, Hungary, August 23-26, 2009

 

Important recent papers

Novel bat herpes- and adenoviruses  2008, 2010 in press

Genome sequencing of non-isolated adenoviruses: 2009, 2010

Siberian sturgeon herpesvirus 2010 self archiving

Human adenovirus (recombination, obesity?)

Catfish herpesvirus 2008

Adenoviruses. General features/Pathogenesis: 2008

Complete genome of snake adenovirus: 2008

Phylogenetic analysis of adenovirus sequences: 2007

New human adenovirus: 2007

New siadenovirus in raptors: 2006  Journal of Avian Medicine and Surgery

First Old World monkey adenovirus genomes: 2004, 2005

Goose reovirus: 2003, 2005

Lizard adenovirus sequences; general adenovirus PCR: 2004

Cell tropism of recombinants using fiber knobs of atadenovirus: 2004

Bovine adenovirus 10: 2004

Snake parvovirus genome: 2004

The genetic content and molecular evolution of adenoviruses: 2003/ J Gen Virol Online

Porcine circovirus: 2002    2003

Molecular evolution of adenoviruses: 2003

Snake and fish adenoviruses2002

The first adenovirus from marsupial (brushtail possum) 2002 pdf

 

Frog adenovirus proves to be similar to that of turkey hemorrhagic enteritis virus: 2000

 

Selected other publications

(click here to get the full list)

 

 

Ivanics E, Palya V, Markos B, Dán A, Ursu K, Harrach B, Kaján G, Glávits R (2010) Hepatitis and hydropericardium syndrome associated with adenovirus infection in goslings.Acta Vet Hung 58. 47-58

Graham DA, Calvert V, Benkö M, Curran W, Wylie M, Snodden DA, Moffet DA, Papp T, Adair BM, Smyth JA (2005) Isolation of bovine adenovirus serotype 6 from a calf in the United Kingdom. Vet Rec 156. 82-86.

Fanigliulo A, Comes S, Pacella R, Harrach B, Martin DP, Crescenzi A (2005) Characterisation of Potato virus Y nnp strain inducing veinal necrosis in pepper: a naturally occurring recombinant strain of PVY. Arch Virol 150. 709-720. (Epub 2004 Dec 10.)

 

Molnár K, Eszterbauer E, Székely Cs, Dán Á, Harrach B (2002) Morphological and molecular biological studies on intramuscular Mxyobolus spp. of cyprinid fish. J. Fish Dis. 25. 1-10

 

Davison AJ, Harrach B (2002): Siadenovirus. Adenoviridae. In Tidona CA, Darai G (eds.) The Springer Index of Viruses, Springer-Verlag, Berlin, Heidelberg, New York, pp. 29-33

 

Harrach B (2002): Aviadenovirus. Adenoviridae. Tidona CA, Darai G (eds.) The Springer Index of Viruses. Springer-Verlag, Berlin, Heidelberg, New York, pp. 9-18

 

Dán Á, Élö P, Harrach B, Zádori Z, Benkö M (2001): Four new inverted terminal repeat sequences from bovine adenoviruses reveal striking differences in the length and content of the ITRs. Virus Genes 22. 175-179

Barbezange, C, Benkö M., Dán, Á., Harrach, B. (2000): DNA sequencing and phylogenetic analysis of the protease gene of ovine adenovirus 3 suggest that adenoviruses of sheep belong to two different genera. Virus Res. 66. 79-80 full text/pdf

Harrach B (2000): Reptile adenoviruses in cattle? Acta Vet Hung 48. 485-490 Full text/pdf

Rusvai M, Harrach B, Bánrévi A, Evans PS, Benkö M (2000) Identification and sequence analysis of the core protein genes of bovine adenovirus 2. Virus Res. 70. 25-30 Full text/pdf

Benkö M, Harrach B (1998) A proposal for establishing a new (third) genus within the Adenoviridae family. Arch Virol 143. 829-837

 

 

Last update by B. Harrach on August 2, 2010

 

To see the location of the last visitors click on the icon and choose ˝By World Map˝!